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KMID : 0857220040080020372
Journal of the Korean Pediatric Cardiology Society
2004 Volume.8 No. 2 p.372 ~ p.378
Percutaneous Closure of Patent Foramen Ovale in Patients With Paradoxical Embolism and Cryptogenic Transient Ischemic Attack or Cerebrovascular Accident
Lee Dong-Jun

Lee Jae-Eun
Cho Do-Jun
Yoo Ki-Yang
Abstract
Purpose: Paradoxical embolism through a patent foramen ovale (PFO) is a well known risk factor for recurrent thromboembolic events. We report the results of transcatheter PFO closure for paradoxical embolism using the PFO Amplazter¨Þ Device.

Methods: Since 2003, total 7 patients who had been treated at the department of neurology with PFO and at least 1 cryptogenic transient ischemic attack or cerebrovascular accident were selected. All patients underwent percutaneous PFO closure using PFO Amplatzer¨Þ Device assisted by transesophageal echocardiography under general anesthesia.

Results: The implantation procedure was successful in all 7 patients. Peri-interventional complication was only transient ST-segment elevation in one case. During mean 9 month(range from 1 to 19 months) follow up, no recurrent thromboembolic events and no residual shunt through PFO were observed.

Conclusion: Percutaneous PFO closure with the PFO Amplatzer¨Þ Device appears to be a reliable technique in the prevention of recurrent systemic thromboembolism in patients with a history of cryptogenic ischemic attack and PFO. Further study is needed to identify patients who are most likely to benefit from this intervention.
KEYWORD
Patent foramen ovale, Transient ischemic attack, Stroke, Device closure
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